Cancer occurrence during follow-up of the CAPP2 study -aspirin use for up to four years significantly reduces Lynch syndrome cancers for up to several years after completion of therapy
نویسندگان
چکیده
Cancer occurrence during follow-up of the CAPP2 study -aspirin use for up to four years significantly reduces Lynch syndrome cancers for up to several years after completion of therapy John Burn, John C Mathers, Anne-Marie Gerdes, MarieLuise Bisgaard, Gareth Evans, Diana Eccles, Annika Lindblom, Findlay Macrae, Eamonn R Maher, Jukka-Pekka Mecklin, Gabriela Moslein, Sylviane Olschwang, Raj Ramesar, Hans FA Vasen, Juul Wijnen, Gail Barker, Faye Elliott, Henry Lynch, D Tim Bishop, the CAPP2 Consortium
منابع مشابه
Bowel cancer chemoprevention - ready for the clinic?
In 1988 Gabriel Kune of Melbourne published a seminal paper reporting a negative association of the use of nonsteroidal anti-inflammatory drugs such as aspirin and colorectal cancer. This prompted a deluge of case control and cohort studies, all but one of which confirmed the finding. The conclusion of these observational studies was that regular aspirin users had half as many cancers. Four ran...
متن کاملLong-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial
BACKGROUND Observational studies report reduced colorectal cancer in regular aspirin consumers. Randomised controlled trials have shown reduced risk of adenomas but none have employed prevention of colorectal cancer as a primary endpoint. The CAPP2 trial aimed to investigate the antineoplastic effects of aspirin and a resistant starch in carriers of Lynch syndrome, the major form of hereditary ...
متن کاملPnm-5: Anti-Mullerian Hormone in The Assessment and follow up of Cancer in Young Females
Background The impact of cancer therapy on the reproductive potential of patients is increasingly recognized because survival rates of patients have clearly improved in recent years. The study stressed the use of AMH may allow better prediction of chemotherapy-related risk to further fertility. MaterialsAndMethods A narrative review was performed within articles published at PubMed, Elsevier, S...
متن کاملRadiation induced myocardial perfusion abnormalities in patients with left breast cancer: A prospective study with short and long term follow up
Introduction:The external beam radiation therapy for patients with left breast cancer at the mastectomy site may cause myocardial perfusion abnormalities. We intended to study the change of these abnormalities at short and long term post radiotherapy follow up. Methods: Twenty patients with left and 20 patients with right breast cancer comprised the exposed an...
متن کاملThe efect of self-healing education on self compassion, body image concern and improvement of disease process in suffering from skin cancers
Background and Aim: The purpose of the present study was to asses a the effect of self-healing education on self compassion, body image, concern and improvement of disease process in women with skin cancer. Methods: A quasi-experimental research with pre-test, post-test and follow up with control group was conducted. The population included all women with skin cancer referring to Shahid Rahi...
متن کامل